Recent articles

• Fuster-Martínez I, Calatayud S. The current landscape of antifibrotic therapy across different organs: A systematic approach. Pharmacol Res. 2024 Jul:205:107245. doi: 10.1016/j.phrs.2024.107245. Epub 2024 May 29.
• Fuster-Martínez I, Català-Senent JF, Hidalgo MR, Roig FJ, Esplugues JV, Apostolova N, García-García F, Blas-García A. Integrated transcriptomic landscape of the effect of anti-steatotic treatments in high-fat diet mouse models of non-alcoholic fatty liver disease. J Pathol. 2024 Jan 5. doi:10.1002/path.6242. Epub online ahead of print.
• Seco-Cervera M, Ortiz-Masiá D, Macias-Ceja DC, Coll S, Gisbert-Ferrándiz L, Cosín-Roger J, Bauset C, Ortega M, Heras-Morán B, Navarro-Vicente F, Millán M, Esplugues JV, Calatayud S, Barrachina MD. Resistance to apoptosis in complicated Crohn’s disease: Relevance in ileal fibrosis. Biochim Biophys Acta Mol Basis Dis. 2024 Feb;1870(2):166966. doi: 10.1016/j.bbadis.2023.166966. Epub 2023 Nov 22.
• Moragrega AB, Gruevska A, Fuster-Martínez I, Benedicto AM, Tosca J, Montón C, Victor VM, Esplugues JV, Blas-García A, Apostolova N. Anti-inflammatory and immunomodulating effects of rilpivirine: Relevance for the therapeutics of chronic liver disease. Biomed Pharmacother. 2023 Nov;167:115537. doi:10.1016/j.biopha.2023.115537. Epub 2023 Sep 20.
• Macias-Ceja DC, Mendoza-Ballesteros MT, Ortega-Albiach M, Barrachina MD, Ortiz-Masià D. Role of the epithelial barrier in intestinal fibrosis associated with inflammatory bowel disease: relevance of the epithelial-to mesenchymal transition. Front Cell Dev Biol. 2023 Sep 26;11:1258843. doi:10.3389/fcell.2023.1258843.
• Lis-López L, Bauset C, Seco-Cervera M, Macias-Ceja D, Navarro F, Álvarez Á, Esplugues JV, Calatayud S, Barrachina MD, Ortiz-Masià D, Cosín-Roger J. P2X7 Receptor Regulates Collagen Expression in Human Intestinal Fibroblasts: Relevance in Intestinal Fibrosis. Int J Mol Sci. 2023 Aug 18;24(16):12936. doi:10.3390/ijms241612936.
• Macias-Ceja DC, Barrachina MD, Ortiz-Masià D. Autophagy in intestinal fibrosis: relevance in inflammatory bowel disease. Front Pharmacol. 2023 Jun 15;14:1170436. doi: 10.3389/fphar.2023.1170436.
• Blanch-Ruíz MA, Sánchez-López A, Ríos-Navarro C, Ortega-Luna R, Collado-Díaz V, Orden S, Martínez-Cuesta MA, Esplugues JV, Álvarez Á. Abacavir causes leukocyte/platelet crosstalk by activating neutrophil P2X7 receptors thus releasing soluble lectin-like oxidized low-density lipoprotein receptor-1. Br J Pharmacol. 2023 Jun;180(11):1516-1532. doi: 10.1111/bph.16016. Epub 2023 Jan 18.
• Busca Arenzana C, González-García J, Blas-García A, Esplugues JV, Olveira Martín A, Montes Ramírez ML. Benefits of rilpivirine for liver stiffness in HIV/HCV-coinfected patients. Enferm Infecc Microbiol Clin (Engl Ed). 2023 Feb 1:S2529-993X(23)00032-1. doi: 10.1016/j.eimce.2022.08.015. Epub 2023 Feb 1.
• Macias-Ceja DC, Barrachina MD, Ortiz-Masià D. Autophagy in intestinal fibrosis: relevance in inflammatory bowel disease. Front Pharmacol. 2023 Jun 15;14:1170436. doi: 10.3389/fphar.2023.1170436.
• Andújar I, Esplugues JV, García-Martínez P. Looking beyond the Skin: Pathophysiology of Cardiovascular Comorbidity in Psoriasis and the Protective Role of Biologics. Pharmaceuticals (Basel). 2022 Sep 3;15(9):1101. doi: 10.3390/ph15091101.
• Macias-Ceja DC, Coll S, Bauset C, Seco-Cervera M, Gisbert-Ferrándiz L, Navarro F, Cosin-Roger J, Calatayud S, Barrachina MD, Ortiz-Masia D. IFNγ-Treated Macrophages Induce EMT through the WNT Pathway: Relevance in Crohn’s Disease. Biomedicines. 2022 May 8;10(5):1093. doi: 10.3390/biomedicines10051093.
• De Marañón AM, Díaz-Pozo P, Canet F, Díaz-Morales N, Abad-Jiménez Z, López-Domènech S, Vezza T, Apostolova N, Morillas C, Rocha M, Víctor VM. Metformin modulates mitochondrial function and mitophagy in peripheral blood mononuclear cells from type 2 diabetic patients. Redox Biol. 2022 Jul;53:102342. doi: 10.1016/j.redox.2022.102342. Epub 2022 May 17.
• Lucantoni F, Benedicto AM, Gruevska A, Moragrega ÁB, Fuster-Martínez I, Esplugues JV, Blas-García A, Apostolova N. Implication of autophagy in the antifibrogenic effect of Rilpivirine: when more is less. Cell Death Dis. 2022 Apr 20;13(4):385. doi: 10.1038/s41419-022-04789-7.
• Bauset C, Lis-Lopez L, Coll S, Gisbert-Ferrándiz L, Macias-Ceja DC, Seco-Cervera M, Navarro F, Esplugues JV, Calatayud S, Ortiz-Masia D, Barrachina MD, Cosín-Roger J. SUCNR1 Mediates the Priming Step of the Inflammasome in Intestinal Epithelial Cells: Relevance in Ulcerative Colitis. Biomedicines. 2022 Feb 24;10(3):532. doi: 10.3390/biomedicines10030532.
• Gruevska A, Moragrega ÁB, Galindo MJ, Esplugues JV, Blas-García A, Apostolova N. Down-Regulation of the Longevity-Associated Protein SIRT1 in Peripheral Blood Mononuclear Cells of Treated HIV Patients. Cells. 2022 Jan 20;11(3):348. doi:10.3390/cells11030348.
• Alegre F, Martí-Rodrigo A, Polo M, Ortiz-Masiá D, Bañuls C, Pinti M, Álvarez Á, Apostolova N, Esplugues JV, Blas-García A. Macrophages Modulate Hepatic Injury Involving NLRP3 Inflammasome: The Example of Efavirenz. Biomedicines. 2022 Jan 5;10(1):109. doi: 10.3390/biomedicines10010109.
• Díaz-Pozo P, Canet F, Grirrane A, Lopez-Domenech S, Herance JR, Apostolova N, Luna-Marco C, Rovira-Llopis S, Marti M, Morillas C, Rocha M, Garcia H, Victor VM. Gold Nanoparticles Supported on Ceria Nanoparticles Modulate Leukocyte-Endothelium Cell Interactions and Inflammation in Type 2 Diabetes. Antioxidants (Basel). 2022 Nov 20;11(11):2297. doi: 10.3390/antiox11112297.
• Blanch-Ruiz MA, Ortega-Luna R, Gómez-García G, Martínez-Cuesta MÁ, Álvarez Á. Role of Neutrophil Extracellular Traps in COVID-19 Progression: An Insight for Effective Treatment. Biomedicines. 2021 Dec 23;10(1):31. doi: 10.3390/biomedicines10010031.
• Cilla A, López-García G, Collado-Díaz V, Amparo Blanch-Ruiz M, Garcia-Llatas G, Barberá R, Martinez-Cuesta MA, Real JT, Álvarez Á, Martínez-Hervás S. Hypercholesterolemic patients have higher eryptosis and erythrocyte adhesion to human endothelium independently of statin therapy. Int J Clin Pract. 2021 Nov;75(11):e14771. doi: 10.1111/ijcp.14771.
• Gómez-Ferrer M, Amaro-Prellezo E, Dorronsoro A, Sánchez-Sánchez R, Vicente Á, Cosín-Roger J, Barrachina MD, Baquero MC, Valencia J, Sepúlveda P. HIF-Overexpression and Pro-Inflammatory Priming in Human Mesenchymal Stromal Cells Improves the Healing Properties of Extracellular Vesicles in Experimental Crohn’s Disease. Int J Mol Sci. 2021 Oct 19;22(20):11269. doi:10.3390/ijms222011269.
• Benedicto AM, Fuster-Martínez I, Tosca J, Esplugues JV, Blas-García A, Apostolova N. NNRTI and Liver Damage: Evidence of Their Association and the Mechanisms Involved. Cells. 2021 Jul 4;10(7):1687. doi: 10.3390/cells10071687. Review.
• Lucantoni F, Martínez-Cerezuela A, Gruevska A, Moragrega ÁB, Víctor VM, Esplugues JV, Blas-García A, Apostolova N. Understanding the implication of autophagy in the activation of hepatic stellate cells in liver fibrosis: are we there yet? J Pathol. 2021 Jul;254(3):216-228. doi: 10.1002/path.5678. Review.
• Blanch-Ruiz MA, Ortega-Luna R, Martínez-Cuesta MÁ, Álvarez Á. The Neutrophil Secretome as a Crucial Link between Inflammation and Thrombosis. Int J Mol Sci. 2021 Apr 17;22(8):4170. doi: 10.3390/ijms22084170.
• Collado-Díaz V, Martinez-Cuesta MÁ, Blanch-Ruiz MA, Sánchez-López A, García-Martínez P, Peris JE, Usach I, Ivorra MD, Lacetera A, Martín-Santamaría S, Esplugues JV, Alvarez A. Abacavir Increases Purinergic P2X7 Receptor Activation by ATP: Does a Pro-inflammatory Synergism Underlie Its Cardiovascular Toxicity? Front Pharmacol. 2021 Mar 31;12:613449. doi: 10.3389/fphar.2021.613449.
• Gruevska A, Moragrega ÁB, Cossarizza A, Esplugues JV, Blas-García A, Apostolova N. Apoptosis of Hepatocytes: Relevance for HIV-Infected Patients under Treatment. Cells. 2021 Feb 16;10(2):410. doi: 10.3390/cells10020410. Review.
• Cosín-Roger J, Ortiz-Masia D, Barrachina MD, Calatayud S. Metabolite Sensing GPCRs: Promising Therapeutic Targets for Cancer Treatment? Cells. 2020 Oct 23;9(11):2345. doi: 10.3390/cells9112345. Review.
• Martí-Masanet M, Codoñer-Franch P, Orden S, Álvarez Á, Esplugues JV, Martí-Cabrera M. Leukocyte-Endothelium Interaction Is Associated with Fat Mass in Children. J Pediatr. 2020 Jun;221:181-187.e1. doi: 10.1016/j.jpeds.2020.02.036.
• Gisbert-Ferrándiz L, Cosin-Roger J, Hernández C, Macias-Ceja DC, Ortiz-Masiá D, Salvador P, Wildenberg ME, Esplugues JV, Alós R, Navarro F, Calatayud S, Barrachina MD. The vitamin D receptor Taq I polymorphism is associated with reduced VDR and increased PDIA3 protein levels in human intestinal fibroblasts. J Steroid Biochem Mol Biol. 2020 Sep;202:105720. doi:10.1016/j.jsbmb.2020.105720. Epub 2020 Jun 18.
• López-Sanromán A, Esplugues JV, Domènech E. Pharmacology and safety of tofacitinib in ulcerative colitis. Gastroenterol Hepatol. 2021 Jan;44(1):39-48. English, Spanish. doi: 10.1016/j.gastrohep.2020.04.012. Epub 2020 Aug 20.
• Ortiz-Masiá D, Gisbert-Ferrándiz L, Bauset C, Coll S, Mamie C, Scharl M, Esplugues JV, Alós R, Navarro F, Cosín-Roger J, Barrachina MD, Calatayud S. Succinate Activates EMT in Intestinal Epithelial Cells through SUCNR1: A Novel Protagonist in Fistula Development. Cells. 2020 Apr 29;9(5). pii: E1104. doi: 10.3390/cells9051104. PubMed PMID: 32365557.
• García-Martínez P, Collado-Díaz V, Mateu-Puchades A, Villarroel-Vicente C, Rovira-Llopis S, Blas-García A, Álvarez Á, Esplugues JV, Andújar I. Differential effects of biologics on psoriasis-related vascular inflammation and risk of thrombosis. J Invest Dermatol. 2020 Apr 17. pii: S0022-202X(20)31369-5. doi: 10.1016/j.jid.2020.02.039. [Epub ahead of print] PubMed PMID: 32311396.
• Gruevska A, Moragrega AB, Galindo MJ, Esplugues JV, Blas-Garcia A, Apostolova N. p53 and p53-related mediators PAI-1 and IGFBP-3 are downregulated in peripheral blood mononuclear cells of HIV-patients exposed to NNRTI. Antiviral Res. 2020 Apr 6:104784. doi: 10.1016/j.antiviral.2020.104784. [Epub ahead of print] PubMed PMID: 32272174.
• Gisbert-Ferrándiz L, Cosín-Roger J, Hernández C, Macias-Ceja DC, Ortiz-Masiá D, Salvador P, Esplugues JV, Hinojosa J, Navarro F, Calatayud S, Barrachina MD. Diminished Vitamin D Receptor Protein Levels in Crohn’s Disease Fibroblasts: Effects of Vitamin D. Nutrients. 2020 Apr 1;12(4). pii: E973. doi: 10.3390/nu12040973. PubMed PMID: 32244667.
• Cosin-Roger J, Ortiz-Masià MD, Barrachina MD. Macrophages as an Emerging Source of Wnt Ligands: Relevance in Mucosal Integrity. Front Immunol. 2019 Sep 24;10:2297. doi: 10.3389/fimmu.2019.02297. eCollection 2019. Review. PubMed PMID: 31608072; PubMed Central PMCID: PMC6769121.
• Martí-Rodrigo A, Alegre F, Moragrega ÁB, García-García F, Martí-Rodrigo P, Fernández-Iglesias A, Gracia-Sancho J, Apostolova N, Esplugues JV, Blas-García A. Rilpivirine attenuates liver fibrosis through selective STAT1-mediated apoptosis in hepatic stellate cells. Gut. 2020 May;69(5):920-932. doi: 10.1136/gutjnl-2019-318372. Epub 2019 Sep 17. PubMed PMID: 31530714.
• Cosin-Roger J, Canet F, Macias-Ceja DC, Gisbert-Ferrándiz L, Ortiz-Masiá D, Esplugues JV, Alós R, Navarro F, Barrachina MD, Calatayud S. Autophagy Stimulation as a Potential Strategy Against Intestinal Fibrosis. Cells. 2019 Sep 13;8(9). pii: E1078. doi: 10.3390/cells8091078. PubMed PMID: 31540207; PubMed Central PMCID: PMC6770118.
• Ortiz-Masià D, Salvador P, Macias-Ceja DC, Gisbert-Ferrándiz L, Esplugues JV, Manyé J, Alós R, Navarro-Vicente F, Mamie C, Scharl M, Cosin-Roger J, Calatayud S, Barrachina MD. WNT2b activates epithelial-mesenchymal transition through FZD4: relevance in penetrating Crohn´s disease. J Crohns Colitis. 2020 Feb 10;14(2):230-239. doi: 10.1093/ecco-jcc/jjz134.
• Martinez-Arroyo O, Gruevska A, Victor VM, González-Polo RA, Yakhine-Diop SMS, Fuentes JM, Esplugues JV, Blas-Garcia A, Apostolova N. Mitophagy in human astrocytes treated with the antiretroviral drug Efavirenz: Lack of evidence or evidence of the lack. Antiviral Res. 2019 Aug;168:36-50. doi: 10.1016/j.antiviral.2019.04.015. Epub 2019 May 8.
• Macias-Ceja DC, Ortiz-Masiá D, Salvador P, Gisbert-Ferrándiz L, Hernández C, Hausmann M, Rogler G, Esplugues JV, Hinojosa J, Alós R, Navarro F, Cosin-Roger J, Calatayud S, Barrachina MD. Succinate receptor mediates intestinal inflammation and fibrosis. Mucosal Immunol. 2019 Jan;12(1):178-187. doi: 10.1038/s41385-018-0087-3. Epub 2018 Oct 2.
• Gisbert-Ferrándiz L, Salvador P, Ortiz-Masiá D, Macías-Ceja DC, Orden S, Esplugues JV, Calatayud S, Hinojosa J, Barrachina MD, Hernández C. A Single Nucleotide Polymorphism in the Vitamin D Receptor Gene Is Associated With Decreased Levels of the Protein and a Penetrating Pattern in Crohn’s Disease. Inflamm Bowel Dis. 2018 Jun 8;24(7):1462-1470. doi: 10.1093/ibd/izy094.
• Vallecillo-Hernández J, Barrachina MD, Ortiz-Masiá D, Coll S, Esplugues JV, Calatayud S, Hernández C. Indomethacin Disrupts Autophagic Flux by Inducing Lysosomal Dysfunction in Gastric Cancer Cells and Increases Their Sensitivity to Cytotoxic Drugs. Sci Rep. 2018 Feb 26;8(1):3593.
• Collado-Diaz V, Andujar I, Sanchez-Lopez A, Orden S, Blanch-Ruiz MA, Martinez-Cuesta MA, Blas-García A, Esplugues JV, Álvarez Á. Abacavir induces arterial thrombosis in a murine model. J Infect Dis. 2018 Jun 20;218(2):228-233. doi: 10.1093/infdis/jiy001.
• Perez IA, Blas-Garcia A, Carmona L, Esplugues JV. Ensuring the Consistency of Biosimilars. Curr Pharm Des. 2017;23(44):6733-6738.
• Rovira-Llopis S, Apostolova N, Bañuls C, Muntané J, Rocha M, Victor VM. Mitochondria, the NLRP3 Inflammasome, and Sirtuins in Type 2 Diabetes: New Therapeutic Targets. Antioxid Redox Signal. 2018 Sep 10;29(8):749-791. doi: 10.1089/ars.2017.7313. Epub 2018 Jan 30. Review.
• Salvador P, Macias-Ceja DC, Gisbert L, Hernández C, Bernardo D, Alos R, Navarro-Vicente F, Esplugues JV, Ortiz-Masiá D, Barrachina MD, Calatayud S. CD16 macrophages mediate fibrosis in inflammatory bowel disease. J Crohns Colitis. 2018 Apr 27;12(5):589-599. doi: 10.1093/ecco-jcc/jjx185.
• Alegre F, Moragrega ÁB, Polo M, Marti-Rodrigo A, Esplugues JV, Blas-Garcia A, Apostolova N. Role of p62/SQSTM1 beyond autophagy: a lesson learned from drug-induced toxicity in vitro. Br J Pharmacol. 2018 Feb;175(3):440-455. doi: 10.1111/bph.14093. Epub 2018 Jan 6.
• Polo M, Alegre F, Moragrega AB, Gibellini L+, Marti-Rodrigo A, Blas-Garcia A, Esplugues JV, Apostolova N. Lon protease: a novel mitochondrial matrix protein in the interconnection between drug-induced mitochondrial dysfunction and endoplasmic reticulum stress. Br J Pharmacol. 2017 Sep 23. doi: 10.1111/bph.14045. [Epub ahead of print]. Colaboración con la University of Modena and Reggio Emilia, Italia.
• Apostolova N, Blas-Garcia A, Galindo MJ, Esplugues JV. Efavirenz: What is known about the cellular mechanisms responsible for its adverse effects. Eur J Pharmacol. 2017 Oct 5;812:163-173. doi: 10.1016/j.ejphar.2017.07.016. Epub 2017 Jul 8. Review.
• Alvarez A, Orden S, Andújar I, Collado-Diaz V, Núñez-Delgado S, Galindo MJ, Estrada V, Apostolova N, Esplugues JV. Cardiovascular toxicity of abacavir: a clinical controversy in need of a pharmacological explanation. AIDS. 2017 Aug 24;31(13):1781-1795.
• Macias-Ceja DC, Cosín-Roger J, Ortiz-Masiá D, Salvador P, Hernández C, Esplugues JV, Calatayud S, Barrachina MD. Autophagy stimulation prevents intestinal mucosal inflammation and ameliorates murine colitis. Br J Pharmacol 2017 2017 Aug;174(15):2501-2511.
• Alvarez A, Rios-Navarro C, Blanch-Ruiz MA, Collado-Diaz V, Andujar I, Martinez-Cuesta MA, Orden S, Esplugues JV. Abacavir induces platelet-endothelium interactions by interfering with purinergic signalling: A step from inflammation to thrombosis. Antiviral Res. 2017 May;141:179-185.
• Escribano-Lopez I, Diaz-Morales N, Rovira-Llopis S, de Marañon AM, Orden S, Alvarez A, Bañuls C, Rocha M, Murphy MP, Hernandez-Mijares A, Victor VM. The mitochondria-targeted antioxidant MitoQ modulates oxidative stress, inflammation and leukocyte-endothelium interactions in leukocytes isolated from type 2 diabetic patients. Redox Biol. 2016 Dec;10:200-205. doi: 10.1016/j.redox.2016.10.017. Colaboración con University of Cambridge.
• Milián L, Peris JE, Gandía P, Andújar I, Pallardó L, Górriz JL, Blas-García A. Tenofovir-induced toxicity in renal proximal tubular epithelial cells: involvement of mitochondria. AIDS. 2017 Jul 31;31(12):1679-1684.
• Chueca E, Apostolova N, Esplugues JV, García-González MA, Lanas Á, Piazuelo E. Proton Pump Inhibitors Display Antitumor Effects in Barrett’s Adenocarcinoma Cells. Front Pharmacol. 2016 Nov 25;7:452. PubMed PMID: 27932981; PubMed Central PMCID: PMC5122752. Colaboración con el Instituto de Investigación Sanitaria Aragón, Zaragoza/Departamento de Medicina, Psiquiatría y Dermatología, Universidad de Zaragoza.
• Hicks DF, Goossens N, Blas-García A, Tsuchida T, Wooden B, Wallace MC, NietoN, Lade A, Redhead B, Cederbaum AI, Dudley JT, Fuchs BC, Lee YA, Hoshida Y, Friedman SL. Transcriptome-based repurposing of apigenin as a potential anti-fibrotic agent targeting hepatic stellate cells. Sci Rep. 2017 Mar 3;7:42563. doi: 10.1038/srep42563. PubMed PMID: 28256512; PubMed Central PMCID:PMC5335661. Colaboración con Icahn School of Medicine at Mount Sinai, Nueva York.
• Cosin-Roger J, Simmen S, Melhem H, Atrott K, Frey-Wagner I, Hausmann M, de Vallière C, Spalinger MR, Spielmann P, Wenger RH, Zeitz J, Vavricka SR, Rogler G, Ruiz PA. Hypoxia ameliorates intestinal inflammation through NLRP3/Mtor down regulation and autophagy activation. Nat Commun. 2017 Jul 24;8(1):98. Colaboración con University Hospital Zurich/University of Zurich.
• Esplugues JV, De Pablo C, Collado-Díaz V, Hernández C, Orden S, Álvarez Á. Interference with purinergic signalling: an explanation for the cardiovascular effect of abacavir? AIDS. 2016 Jun 1;30(9):1341-51.
• Macias-Ceja DC, Cosín-Roger J, Ortiz-Masiá D, Salvador P, Hernández C, Calatayud S, Esplugues JV, Barrachina MD. The flesh ethanolic extract of Hylocereus polyrhizus exerts anti-inflammatory effects and prevents murine colitis. Clin Nutr. 2016 Dec;35(6):1333-1339.
• Blas-García A, Apostolova N, Valls-Bellés V, Esplugues JV. Endoplasmic Reticulum and Mitochondria: Independent Roles and Crosstalk in Fatty Liver Diseases and Hepatic Inflammation. Curr Pharm Des. 2016;22(18):2607-18. Review.
• Miova B, Dimitrovska M, Dinevska-Kjovkarovska S, Esplugues JV, Apostolova N. The Heat Stress Response and Diabetes: More Room for Mitochondrial Implication. Curr Pharm Des. 2016;22(18):2619-39. Review. Colaboración con University “St Cyril and Methodius”, Skopje (República de Macedonia).
• Ortiz-Masiá D, Cosín-Roger J, Calatayud S, Hernández C, Alós R, Hinojosa J, Esplugues JV, Barrachina MD. M1 Macrophages Activate Notch Signalling in Epithelial Cells: Relevance in Crohn’s Disease. J Crohns Colitis. 2016 May;10(5):582-92.
• Cosín-Roger J, Ortiz-Masiá D, Calatayud S, Hernández C, Esplugues JV, Barrachina MD. The activation of Wnt signaling by a STAT6-dependent macrophage phenotype promotes mucosal repair in murine IBD. Mucosal Immunol. 2016 Jul;9(4):986-98.
• Hernández C, Barrachina MD, Vallecillo-Hernández J, Álvarez Á, Ortiz-Masiá D, Cosín-Roger J, Esplugues JV, Calatayud S. Aspirin-induced gastrointestinal damage is associated with an inhibition of epithelial cell autophagy. J Gastroenterol. 2016 Jul;51(7):691-701.
• de Vallière C, Cosin-Roger J, Simmen S, Atrott K, Melhem H, Zeitz J, Madanchi M, Tcymbarevich I, Fried M, Kullak-Ublick GA, Vavricka SR, Misselwitz B, Seuwen K, Wagner CA, Eloranta JJ, Rogler G, Ruiz PA. Hypoxia Positively Regulates the Expression of pH-Sensing G-Protein-Coupled Receptor OGR1 (GPR68). Cell Mol Gastroenterol Hepatol. 2016 Jun 25;2(6):796-810. Con University Hospital Zurich/University of Zurich.
• Klionsky DJ et al., incluyendo Apostolova N, Barrachina MD, Calatayud S, and Cossarizza A. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016;12(1):1-222. doi: 10.1080/15548627.2015.1100356. Erratum in: Autophagy. 2016;12(2):443. Selliez, Iban [corrected to Seiliez, Iban].
• Victor VM, Rovira-Llopis S, Bañuls C, Diaz-Morales N, Martinez de Marañon A, Rios-Navarro C, Alvarez A, Gomez M, Rocha M, Hernández-Mijares A. Insulin Resistance in PCOS Patients Enhances Oxidative Stress and Leukocyte Adhesion: Role of Myeloperoxidase. PLoSOne. 2016 Mar 23;11(3):e0151960.
• Meier R, Lutz C, Cosín-Roger J, Fagagnini S, Bollmann G, Hünerwadel A, Mamie C, Lang S, Tchouboukov A, Weber FE, Weber A, Rogler G, Hausmann M. Decreased Fibrogenesis After Treatment with Pirfenidone in a Newly Developed Mouse Model of Intestinal Fibrosis. Inflamm Bowel Dis. 2016 Mar;22(3):569-82. Colaboración con University Hospital Zurich/University of Zurich.