El candidato se incorporará a la Unidad de Farmacología Digestiva e Inflamatoria del Departamento de Farmacología de la Facultad de Medicina y Odontología de la Universitat de València, dentro de la línea de investigación liderada por la Prof. Ángeles Álvarez Ribelles y el Dr. Víctor Collado Díaz.Nuestra línea de investigación se centra en el estudio de nuevos biomarcadores y potenciales dianas terapéuticas en fibrosis e insuficiencia cardíaca, utilizando modelos in vitro, in vivo y muestras de pacientes. Se emplearán técnicas como PCR en tiempo real, citometría de flujo, proteómica (ELISA múltiplex) y RNA-seq. Buscamos un candidato con una gran motivación por la ciencia, que esté dispuesto a trabajar en un ambiente multidisciplinar y […]
Línea de investigación El grupo investiga los mecanismos celulares, epigenéticos y metabólicos que provocan el cáncer colorrectal y tumores pediátricos raros, como el hepatoblastoma. Mediante tecnologías de vanguardia, como la transcriptómica espacial y de single cell, el perfilado de exosomas o el análisis del microbioma y el metaboloma, exploramos cómo la edad, la plasticidad celular o el microambiente tumoral, son capaces de influir en la progresión del cáncer y la resistencia al tratamiento. Nuestro objetivo es identificar nuevos biomarcadores y dianas terapéuticas que sirvan de guía para intervenciones personalizadas y mínimamente invasivas en pacientes de todas las edades. Nuestro laboratorio combina la investigación básica con su impacto traslacional, tendiendo puentes […]
Research line The laboratory investigates the cellular, epigenetic and metabolic mechanisms underlying colorectal cancer and rare pediatric tumors, such as hepatoblastoma. Using cutting-edge technologies, including spatial and single-cell transcriptomics, exosome profiling, and microbiome and metabolome analyses, we explore how factors such as age, cellular plasticity, and the tumor microenvironment influence cancer progression and resistance to treatment. Our objective is to identify novel biomarkers and therapeutic targets to guide personalized and minimally invasive interventions in patients of all ages. Our laboratory combines basic research with a strong translational focus, bridging molecular knowledge and clinical innovation. The candidate will be integrated into the Joint Research Unit in Biomedicine and Pharmacology FISABIO–Dr. Peset […]
Research LineThe selected candidate will join the Digestive and Inflammatory Pharmacology Unit of the Department of Pharmacology, Faculty of Medicine and Dentistry, University of Valencia, within the research line led by Prof. Ángeles Álvarez Ribelles and Dr. Víctor Collado Díaz.Our research focuses on the study of novel biomarkers and potential therapeutic targets in cardiac fibrosis and heart failure, using in vitro and in vivo models, as well as patient samples. Techniques to be used include real-time PCR, flow cytometry, proteomics (multiplex ELISA), and RNA sequencing (RNA-seq). Candidate Profile PhD in Health Sciences (awarded from 2022 onwards). Competitive CV:Publications within the last five years as first and/or corresponding author in first-quartile/first-decile journals (Journal Citation […]
The Academy of Pharmacy of the Valencian Community has awarded the AFCV 2024 Doctoral Thesis prize to Dr. Ángela Moragrega Escolano, for her thesis “Study of the anti-inflammatory and antifibrotic response of rilpivirine in non-parenchymal liver cells”, directed by Ana Blas-Gracia, Nadezda Apostolova and Juan Vicente Esplugues. Congratulate Ángela on Facebook
Congratulations to Sandra Coll Puig, who recently defended superbly her doctoral thesis “Study of etiopathogenic mechanisms modulating endothelial function in Crohn’s disease“, supervised by Sara Calatayud Romero. Congratulate Sandra on Facebook
Enhorabuena a nuestra compañera Nadezda Apostolova, quien recientemente se convirtió en Catedrática de Farmacología de la Universidad de Valencia. Congratulate Nadezda on Facebook
More information here.
Congratulations to our colleague Ana María Benedicto Elena, who has defended beautifully her doctoral thesis “Characterisation of the anti-fibrogenic effect of rilpivirine in liver fibrosis: impact on stellate cell phenotype and communication.” Congratulate Ana María on Facebook
Congratulations to our colleague Raquel Ortega Luna for the excellent defence of her thesis “Study of the effect of the drugs losartan and nintedanib on cardiac fibrosis.” Congratulate Raquel on Facebook
