In our article recently published in J Steroid Biochem Mol Biol – a collaboration with Tytgat Institute for Liver and Intestinal Research (Amsterdam UMC, University of Amsterdam), Hospital La Fe and Hospital Manises – we show that treatment with vitamin D increases levels of its receptor and attenuates the proliferation of fibroblasts in Crohn’s disease. The Vitamin D Receptor Taq I Polymorphism Is Associated With Reduced VDR and Increased PDIA3 Protein Levels in Human Intestinal Fibroblasts Fibroblast viewed through a miscroscope
The project has been awarded to the line led by Dras. Barrachina and Calatayud.
Succinate Activates EMT in Intestinal Epithelial Cells through SUCNR1: A Novel Protagonist in Fistula Development.
Differential effects of biologics on psoriasis-related vascular inflammation and risk of thrombosis
p53 and p53-related Mediators PAI-1 and IGFBP-3 Are Downregulated in Peripheral Blood Mononuclear Cells of HIV-patients Exposed to NNRTI.
Diminished Vitamin D Receptor Protein Levels in Crohn’s Disease Fibroblasts: Effects of VD.
We are looking for PhD students to join our line of research on mechanisms of mucosal recovery and progression to fibrosis in inflammatory bowel disease.
Our colleague Laura Gisbert Ferrándiz has defended her thesis.
We are excited to announce the International Workshop on Liver and Gut Fibrosis, which will take place in Valencia, on 18-19th June this year.
Rilpivirine attenuates liver fibrosis through selective STAT1-mediated apoptosis in hepatic stellate cells.