Seminar given by our colleague, Dr. Federico Lucantoni https://ir.uv.es/microsucim
Congratulations to Jesús Cosín Roger, member of our group, who has been awarded the XXXVII Young Researcher Award by the Spanish Society of Pharmacology. This award is granted to researchers aged 35 years or younger with an outstanding scientific career.
Our postgraduate researcher Mariam Blanch has been awarded the EMBO Scientific Exchange Grant to carry out a research stay in the laboratory of Dr. Clare Pridans, at the Centre for Inflammation Research, University of Edinburgh. Mariam will participate in the project “Development of a monocytopenic model testing different CSF1R inhibitors to study the physiology of thrombus formation”.
Our postgraduate researcher Aleksandra Gruevska has been awarded the EMBO Short-Term Fellowship to carry out a research stay in the laboratory of Professor Fabio Marra, in the Department of Experimental and Clinical Medicine, University of Florence, Italy. Aleksandra will study the antiretroviral drug Rilpivirine’s effect on the fibrogenic phenotype of human hepatic stellate cells.
In this review, we discuss relevant recent studies of the role of autophagy in hepatic stellate cell activation.
This review studies the structure, activation pathways, and specific cellular location of P2X7R in order to analyze its biological relevance. It points to a possible allosteric modulation of this receptor by endogenous mediators, which would turn the tiny regulated ATP inputs into an activated functional P2X7R signaling, supporting the relevance of this receptor in a non-damaged tissue.
In our review in Cells we discuss the evidence regarding apoptosis of hepatocytes induced by HIV, HIV-encoded proteins, or cART.
We just published “Metabolomics as a Promising Resource Identifying Potential Biomarkers for Inflammatory Bowel Disease”.
Would you like to contribute to a special issue of Cells: Anti-HIV Therapy and Chronic Liver Diseases? Send proposals to to nadezda.apostolova@uv.es (Guest Editor) More information
In our article recently published in J Steroid Biochem Mol Biol – a collaboration with Tytgat Institute for Liver and Intestinal Research (Amsterdam UMC, University of Amsterdam), Hospital La Fe and Hospital Manises – we show that treatment with vitamin D increases levels of its receptor and attenuates the proliferation of fibroblasts in Crohn’s disease. The Vitamin D Receptor Taq I Polymorphism Is Associated With Reduced VDR and Increased PDIA3 Protein Levels in Human Intestinal Fibroblasts Fibroblast viewed through a miscroscope