This review studies the structure, activation pathways, and specific cellular location of P2X7R in order to analyze its biological relevance. It points to a possible allosteric modulation of this receptor by endogenous mediators, which would turn the tiny regulated ATP inputs into an activated functional P2X7R signaling, supporting the relevance of this receptor in a non-damaged tissue.
- Our PhD student Aleksandra Gruevksa has defended her thesis “Intercommunications among inflammation, chronic liver disease and HIV:understanding the hepatoprotective effects of the antiretroviral drug rilpivirine”.
- Ciencia i canyes
- Our colleague Ainhoa Sánchez has defended her doctoral thesis “Study of the mechanism responsible for the prothrombotic effect of Abacavir”.
- Seminar Thursday 18th November 2021 :”To microscope or not to microscope: a few applications to analyse autophagy and mitochondrial biology in live cells.”
- Young Researcher Award, Spanish Society of Pharmacology
abacavir acif antiretrovirals cerebral-vascular damage cGKI chronic liver disease ciberehd colon Crohn's disease designations doctoral prize doctoral studies efavirenz excellence research group fibroblast fibrosis fibrostat fpi fpu gut hiv hospital de manises hospital universitario dr. peset hospital universitario y politécnico la fe incorporations inflammatory bowel disease liver liver injury macrophages master degree mitophagy newspapers and journals p2x7 pharmacology prometeo programme psoriasis rilpivirina stem cells sucnr1 technician thrombosis tytgat institute for liver and intestinal research university of zurich vascular reactivity vitamin d