Our article published recently in the British Journal of Pharmacology

Our article published recently in the British Journal of Pharmacology

In our article published recentlyin the British Journal of Pharmacology, “Abacavir causes leukocyte/platelet crosstalk by neutrophil P2X7 receptor release of sLOX” we analyze the role of neutrophils–and specifically the secretomereleased by abacavir-treatedneutrophils – in the platelet activation that precedes thrombosis. We have observed that neutrophils are target cells in abacavir-induced thrombosis and that sLOX-1 could be the missing link in abacavir-associated cardiovascular risk.

New article in J Steroid Biochem Mol Biol

New article in J Steroid Biochem Mol Biol

In our article recently published in J Steroid Biochem Mol Biol – a collaboration with Tytgat Institute for Liver and Intestinal Research (Amsterdam UMC, University of Amsterdam), Hospital La Fe and Hospital Manises – we show that treatment with vitamin D increases levels of its receptor and attenuates the proliferation of fibroblasts in Crohn’s disease. The Vitamin D Receptor Taq I Polymorphism Is Associated With Reduced VDR and Increased PDIA3 Protein Levels in Human Intestinal Fibroblasts Fibroblast viewed through a miscroscope