In this article (a study in collaboration with the University of Zurich and Hospital Dr. Peset, Hospital La Fe and Hospital de Manises, in Valencia) we demonstrate that the succinate receptor SUCNR1 is increased in Crohn’s patients with fistulas, and that this receptor mediates a process involved in the development of fistulas called epithelial-mesenchymal transition. Our results endorse SUCNR1 as a new pharmacological target for the treatment of complications associated with Crohn’s patients.
